Pesquisa sobre:
INTERFERON REGULATORY FACTOR-3
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Interferon Regulatory Factor-3
Descritor
Espanhol
:
Factor 3 Regulador del Interferón
Descritor
Português
:
Fator Regulador 3 de Interferon
Sinônimos
Inglês
:
IRF-3 Transcription Factor
Categoria:
D12.644.360.024.302.374
D12.776.157.057.050.374
D12.776.260.504.374
D12.776.476.024.385.374
D12.776.744.562
D12.776.930.332.374
Definição
Inglês
:
An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral
infection
.
PHOSPHORYLATION
of IRF-3 causes the protein to be translocated from the
CYTOPLASM
to
CELL NUCLEUS
where it binds DNA, and activates transcription.
Nota Histórica
Inglês
:
2006(1996)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
50777
Identificador Único:
D050838
Ocorrência na BVS
:
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CID-10
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